| Fatty acid compositions of plasma lipids in atopic dermatitis/asthma patients. | |
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MedLine Citation:
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PMID: 8147707 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The proportions of linoleic acid in total plasma lipids and phospholipids were significantly greater and those of oleic acid were lower in pre-puberal and puberal atopic patients as compared with age-matched healthy controls. The n-3/n-6 fatty acid ratio of the triacylglycerol fraction was also lower in atopic patients. However, no significant decreases in the proportions of dihomo-gamma-linolenic acid and arachidonic acid were observed in plasma lipids of atopic patients, suggesting that delta 6-desaturase activity is not impaired in atopic patients. We provide an explanation for the beneficial effects of raising the n-3/n-6 ratio of dietary oils in the context of suppressing allergic hyper-reactivity in humans. |
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Authors:
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K Sakai; H Okuyama; H Shimazaki; M Katagiri; S Torii; T Matsushita; S Baba |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Arerugī = [Allergy] Volume: 43 ISSN: 0021-4884 ISO Abbreviation: Arerugi Publication Date: 1994 Jan |
Date Detail:
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Created Date: 1994-05-04 Completed Date: 1994-05-04 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0241212 Medline TA: Arerugi Country: JAPAN |
Other Details:
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Languages: eng Pagination: 37-43 Citation Subset: IM |
Affiliation:
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Faculty of Pharmaceutical Sciences, Nagoya City University. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Asthma / blood*, diet therapy Child Dermatitis, Atopic / blood*, diet therapy Fatty Acids / analysis* Fatty Acids, Omega-3 / administration & dosage, analysis Humans Linoleic Acid Linoleic Acids / analysis Lipids / blood* Oleic Acid Oleic Acids / analysis Phospholipids / blood Triglycerides / blood |
| Chemical | |
Reg. No./Substance:
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0/Fatty Acids; 0/Fatty Acids, Omega-3; 0/Linoleic Acids; 0/Lipids; 0/Oleic Acids; 0/Phospholipids; 0/Triglycerides; 112-80-1/Oleic Acid; 2197-37-7/Linoleic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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