Document Detail

Fatty acid composition of serum lipids: is this marker of fat intake still relevant for identifying metabolic and cardiovascular disorders?
MedLine Citation:
PMID:  14717056     Owner:  NLM     Status:  MEDLINE    
Analysis of the fatty acid composition of serum lipid fractions is an old but still useful method for several purposes. The proportions of essential polyunsaturated and trans fatty acids are biomarkers of dietary intake that can be used to improve estimates of fatty acid intake in dietary trials and population studies. Furthermore, the metabolism of essential n-6 and n-3 fatty acids is reflected in the serum fatty acid composition. Changes in the activity of the delta-6 and delta-5 desaturases, which affect the proportions of dihomogamma-linolenic acid and arachidonic acid in serum lipids, are associated with insulin resistance and may explain differences in coronary heart disease risk.
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Publication Detail:
Type:  Comment; Editorial; Review    
Journal Detail:
Title:  Nutrition, metabolism, and cardiovascular diseases : NMCD     Volume:  13     ISSN:  0939-4753     ISO Abbreviation:  Nutr Metab Cardiovasc Dis     Publication Date:  2003 Oct 
Date Detail:
Created Date:  2004-01-13     Completed Date:  2004-04-05     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9111474     Medline TA:  Nutr Metab Cardiovasc Dis     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  253-5     Citation Subset:  IM    
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MeSH Terms
Biological Markers / blood*
Cardiovascular Diseases / blood,  diagnosis*
Dietary Fats / administration & dosage*
Fatty Acids / blood*
Linoleic Acid / metabolism
Lipids / blood*
Reg. No./Substance:
0/Biological Markers; 0/Dietary Fats; 0/Fatty Acids; 0/Lipids; 2197-37-7/Linoleic Acid
Comment On:
Nutr Metab Cardiovasc Dis. 2003 Oct;13(5):256-66   [PMID:  14717057 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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