| Fatty acid composition of plasma lipids in acrodermatitis enteropathica before and after zinc supplementation. | |
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MedLine Citation:
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PMID: 3987733 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The fatty acid composition of different plasma lipid fractions has been estimated in a 6-month-old girl with acrodermatitis enteropathica before and after zinc supplementation. Linoleic acid and its metabolites were extremely reduced in triglycerides and sterol-esters. In contrast, n-3-fatty acids were increased in sterol-esters and phospholipids. Zinc supplementation led to quick clinical improvement, and linoleic and arachidonic acid increased rapidly in triglycerides and sterol-esters to the values of healthy infants. Fatty acids of phospholipids remained relatively stable. Our findings could be explained by impaired enteral absorption of linoleic acid. Further attention should be directed to the supply and metabolism of essential fatty acids in acrodermatitis enteropathica. |
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Authors:
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B Koletzko; A Bretschneider; H J Bremer |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: European journal of pediatrics Volume: 143 ISSN: 0340-6199 ISO Abbreviation: Eur. J. Pediatr. Publication Date: 1985 Mar |
Date Detail:
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Created Date: 1985-06-20 Completed Date: 1985-06-20 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7603873 Medline TA: Eur J Pediatr Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 310-4 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acrodermatitis
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blood*,
drug therapy Fatty Acids, Essential / blood* Female Humans Infant Intestinal Absorption Linoleic Acid Linoleic Acids / blood, metabolism Lipids / blood* Phospholipids / blood Sterols / blood Triglycerides / blood Zinc / therapeutic use* |
| Chemical | |
Reg. No./Substance:
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0/Fatty Acids, Essential; 0/Linoleic Acids; 0/Lipids; 0/Phospholipids; 0/Sterols; 0/Triglycerides; 2197-37-7/Linoleic Acid; 7440-66-6/Zinc |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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