| Fatigue in out-patients with inflammatory bowel disease is common and multifactorial. | |
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MedLine Citation:
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PMID: 22059387 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Background Patients with inflammatory bowel disease (IBD) often complain of fatigue. Aim To investigate the prevalence and characteristics of fatigue among IBD out-patients in Scandinavia and to provide normative values for fatigue in IBD patients. Methods A cross-sectional study was conducted on 425 IBD patients from six out-patient centres in Denmark, Norway and Sweden. Fatigue was measured using the Multidimensional Fatigue Inventory. The patients were also screened for anaemia and iron deficiency. Each centre included approximately 5% of their IBD cohort. The patients were enrolled consecutively from the out-patient clinics, regardless of disease activity and whether the visit was scheduled. The fatigue analysis was stratified for age and gender. Results Using the 95th percentile of the score of the general population as a cut-off, approximately 44% of the patients were fatigued. When comparing the IBD patients with disease activity to the IBD patients in remission, all dimensions of fatigue were statistically significant (P < 0.05). Being anaemic or iron deficient was not associated with increased fatigue. Being a male patient with ulcerative colitis treated with corticosteroids was a strong determinant for increased fatigue. The normative ranges for IBD fatigue were calculated. Conclusions Fatigue in IBD is common regardless of anaemia or iron deficiency. Fatigue in IBD is most marked for patients <60 years of age. Stratifying for gender and age is necessary when analysing fatigue, as fatigue is expressed differently between groups. |
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Authors:
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P Bager; R Befrits; O Wikman; S Lindgren; B Moum; H Hjortswang; N H Hjollund; J F Dahlerup |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-11-7 |
Journal Detail:
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Title: Alimentary pharmacology & therapeutics Volume: - ISSN: 1365-2036 ISO Abbreviation: - Publication Date: 2011 Nov |
Date Detail:
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Created Date: 2011-11-8 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8707234 Medline TA: Aliment Pharmacol Ther Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© 2011 Blackwell Publishing Ltd. |
Affiliation:
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Department of Medicine V (Hepatology and Gastroenterology), Aarhus University Hospital, Aarhus, Denmark. Department of Gastroenterology and Hepatology, Karolinska University Hospital, Stockholm, Sweden. Department of Medicine, Stockholm South General Hospital, Stockholm, Sweden. Department of Clinical Sciences, Lund University, Gastroenterology-Hepatology Division, Malmö University Hospital, Malmö, Sweden. Department of Gastroenterology, Oslo University Hospital, Oslo, Norway. Department of Endocrinology and Gastroenterology, Linköping University Hospital, Linköping, Sweden. Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark. Department of Occupational Medicine, Hospital Unit Western Jutland, Herning, Denmark. |
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