| Fatigue in multiple sclerosis: cross-sectional correlation with brain MRI findings in 71 patients. | |
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MedLine Citation:
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PMID: 10496289 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Fatigue is an unexplained but common and disabling symptom in MS. We assessed fatigue in 71 patients with MS and identified MS-fatigue (MSF) and MS-nonfatigue (MSNF) groups. Fatigue severity did not correlate with regional or global MRI plaque load or atrophy assessed by conventional sequences. No significant differences were noted in any MRI measures between MSF and MSNF groups. We suggest that brain MRI disease topography or severity does not explain fatigue in MS and that fatigue is likely due to mechanisms poorly characterized by conventional MRI. |
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Authors:
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R Bakshi; R S Miletich; K Henschel; Z A Shaikh; V Janardhan; M Wasay; L M Stengel; R Ekes; P R Kinkel |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Neurology Volume: 53 ISSN: 0028-3878 ISO Abbreviation: Neurology Publication Date: 1999 Sep |
Date Detail:
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Created Date: 1999-11-15 Completed Date: 1999-11-15 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0401060 Medline TA: Neurology Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1151-3 Citation Subset: AIM; IM |
Affiliation:
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Dent Neurologic Institute, Kaleida Health-Millard Fillmore Hospital, Department of Neurology, State University of New York at Buffalo, School of Medicine and Biomedical Sciences, USA. rbakshi@buffalo.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Brain / pathology Fatigue / etiology, pathology* Female Humans Magnetic Resonance Imaging Male Multiple Sclerosis / complications, pathology* |
| Comments/Corrections | |
Comment In:
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Neurology. 2000 Apr 25;54(8):1709-10
[PMID:
10762529
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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