| Fatigue in amyotrophic lateral sclerosis. | |
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MedLine Citation:
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PMID: 18625414 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Fatigue is a common and potentially debilitating symptom of amyotrophic lateral sclerosis (ALS). Questionnaire studies show that ALS subjects have increased subjective fatigue. Physiologic studies demonstrate that ALS subjects have increased physical fatigue, both central and peripheral in origin. No treatment has been proved effective through evidence-based medicine; however, modafinil (Provigil) may be a helpful pharmacologic treatment. Palliative care measures, such as noninvasive ventilation and high-frequency chest wall oscillation, may also reduce fatigue. |
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Authors:
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Jau-Shin Lou |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Physical medicine and rehabilitation clinics of North America Volume: 19 ISSN: 1047-9651 ISO Abbreviation: Phys Med Rehabil Clin N Am Publication Date: 2008 Aug |
Date Detail:
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Created Date: 2008-07-15 Completed Date: 2008-09-19 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9102787 Medline TA: Phys Med Rehabil Clin N Am Country: United States |
Other Details:
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Languages: eng Pagination: 533-43, ix Citation Subset: IM |
Affiliation:
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ALS Center of Oregon, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, CR120, Portland, OR 97239, USA. louja@ohsu.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Amyotrophic Lateral Sclerosis
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physiopathology* Disease Progression Humans Muscle Fatigue / physiology* Prognosis Quality of Life Severity of Illness Index |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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