Document Detail


Fatigue in Parkinson's disease.
MedLine Citation:
PMID:  21635199     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Non-motor symptoms of Parkinson's disease (PD) have become increasingly recognized as central to the disease. These include somatic symptoms, such as pain and autonomic dysfunction (bladder dysfunction, constipation, dipahoresis and orthostatic hypotension) and behavioral problems, such as dementia, depression, fatigue, sleep disorders and psychosis. Research on fatigue has focused on its epidemiology with only a single report of a beneficial treatment trial, which used methylphenidate. AREAS COVERED: This review was made of all articles related to fatigue in Parkinson's disease arising in PUBMED. It will cover the types of fatigue, epidemiology, pathophysiology and treatment of fatigue in PD. EXPERT OPINION: Fatigue is a common and severe problem in Parkinson's disease. Virtually nothing is known about it aside from its epidemiology. It is an area greatly in need of investigation.
Authors:
Joseph H Friedman; Ana Abrantes; Lawrence H Sweet
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Publication Detail:
Type:  Journal Article; Review     Date:  2011-06-03
Journal Detail:
Title:  Expert opinion on pharmacotherapy     Volume:  12     ISSN:  1744-7666     ISO Abbreviation:  Expert Opin Pharmacother     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-08-08     Completed Date:  2012-02-03     Revised Date:  2013-05-20    
Medline Journal Info:
Nlm Unique ID:  100897346     Medline TA:  Expert Opin Pharmacother     Country:  England    
Other Details:
Languages:  eng     Pagination:  1999-2007     Citation Subset:  IM    
Affiliation:
Movement Disorders Program, Butler Hospital, 345 Blackstone Blvd., Providence, RI 02906, USA. joseph_friedman@brown.edu
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MeSH Terms
Descriptor/Qualifier:
Fatigue / etiology*,  physiopathology*,  therapy
Humans
Parkinson Disease / complications*,  physiopathology*,  therapy
Randomized Controlled Trials as Topic

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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