Document Detail

Fatigue crack propagation rates in PMMA bone cement cannot be reduced to a single power law.
MedLine Citation:
PMID:  18161813     Owner:  NLM     Status:  MEDLINE    
Cement mantles around metallic implants have pre-existing flaws (shrinkage induced cracks, laminations, and endosteal surface features) and their fatigue failure is related to the fatigue crack propagation (FCP) rate of bone cement. We estimated the relevant in vivo range of cyclic stress intensity factor (DeltaK) around a generic femoral stem (0-1 MPa square root(m)) and determined that previous FCP data did not adequately cover this range of DeltaK. Vacuum-mixed standard bone cement was machined into ASTM E647 standard compact notched tension specimens. These were subject to sinusoidal loading (R = 0.1) at 5 Hz in 37 degrees C DI water, covering a DeltaK range of 0.25-1.5 MPa square root(m) (including a decreasing DeltaK protocol). FCP-rate data is normally reduced to a power-law fit relating crack growth rate (da/dn) to DeltaK. However, a substantial discontinuity was observed in our data at around DeltaK = 1, so two power-law fits were used. Over the physiologically plausible range of DeltaK, cracks grew at a rate of 2.9 E -8 x DeltaK(2.6) m/cycle. Our data indicated that FCP-rates for 0.5 > DeltaK > 0.3 MPa square root(m) are between 10 E -8 and 10 E -8 m/cycle, 1 or 2 orders of magnitude greater than predicted by extrapolating from previous models based on higher DeltaK data.
Amos Race; Kenneth A Mann
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  Journal of biomedical materials research. Part B, Applied biomaterials     Volume:  86     ISSN:  1552-4981     ISO Abbreviation:  J. Biomed. Mater. Res. Part B Appl. Biomater.     Publication Date:  2008 Jul 
Date Detail:
Created Date:  2008-06-23     Completed Date:  2008-11-24     Revised Date:  2010-01-06    
Medline Journal Info:
Nlm Unique ID:  101234238     Medline TA:  J Biomed Mater Res B Appl Biomater     Country:  United States    
Other Details:
Languages:  eng     Pagination:  278-82     Citation Subset:  IM    
Copyright Information:
2007 Wiley Periodicals, Inc.
Musculoskeletal Science Research Center, Institute for Human Performance, SUNY Upstate Medical University, 750 East Adams Street, Syracuse, New York 13210, USA.
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MeSH Terms
Biocompatible Materials / chemistry*
Bone Cements / chemistry*
Compressive Strength
Hip Prosthesis*
Materials Testing
Models, Theoretical
Polymethyl Methacrylate / chemistry*
Prosthesis Failure
Stress, Mechanical
Tensile Strength
Grant Support
Reg. No./Substance:
0/Biocompatible Materials; 0/Bone Cements; 9011-14-7/Polymethyl Methacrylate

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