Document Detail


Fate of triclosan and evidence for reductive dechlorination of triclocarban in estuarine sediments.
MedLine Citation:
PMID:  18605588     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The biocides triclosan and triclocarban are wastewater contaminants whose occurrence and fate in estuarine sediments remain unexplored. We examined contaminant profiles in 137Cs/7Be-dated sediment cores taken near wastewater treatment plants in the Chesapeake Bay watershed (CB), Maryland and Jamaica Bay(JB), New York. In JB, biocide occurrences tracked the time course of biocide usage and wastewater treatment strategies employed, first appearing in the 1950s (triclocarban) and 1960s (triclosan), and peaking in the late 1960s and 1970s (24 +/- 0.54 and 0.8 +/- 0.4 mg/kg dry weight, respectively). In CB, where the time of sediment accumulation was not as well constrained by 137Cs depth profiles, triclocarban was only measurable in 137Cs-bearing sediments, peaking at 3.6 +/- 0.6 mg/ kg midway through the core and exceeding 1 mg/kg in recent deposits. In contrast, triclosan concentrations were low or not detectable in the CB core. Analysis of CB sediment by tandem mass spectrometry produced the first evidence for complete sequential dechlorination of triclocarban to the transformation products dichloro-, monochloro-, and unsubstituted carbanilide, which were detected at maxima of 15.5 +/- 1.8, 4.1 +/- 2.4, and 0.5 +/- 0.1 mg/kg, respectively. Concentrations of all carbanilide congeners combined were correlated with heavy metals (R2 > 0.64, P < 0.01), thereby identifying wastewater as the principal pathway of contamination. Environmental persistence over the past 40 years was observed for triclosan and triclocarban in JB, and for triclocarban's diphenylurea backbone in CB sediments.
Authors:
Todd R Miller; Jochen Heidler; Steven N Chillrud; Amelia DeLaquil; Jerry C Ritchie; Jana N Mihalic; Richard Bopp; Rolf U Halden
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Environmental science & technology     Volume:  42     ISSN:  0013-936X     ISO Abbreviation:  Environ. Sci. Technol.     Publication Date:  2008 Jun 
Date Detail:
Created Date:  2008-07-08     Completed Date:  2008-10-10     Revised Date:  2010-09-22    
Medline Journal Info:
Nlm Unique ID:  0213155     Medline TA:  Environ Sci Technol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  4570-6     Citation Subset:  IM    
Affiliation:
Center for Water and Health, Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland 21205, USA.
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MeSH Terms
Descriptor/Qualifier:
Carbanilides / chemistry*
Cesium Radioisotopes / chemistry
Chlorine / chemistry*
Geologic Sediments / chemistry*
Oxidation-Reduction
Triclosan / chemistry*
Grant Support
ID/Acronym/Agency:
1R01ES015445/ES/NIEHS NIH HHS; ES007384/ES/NIEHS NIH HHS; ES09089/ES/NIEHS NIH HHS; R01 ES015445-02/ES/NIEHS NIH HHS
Chemical
Reg. No./Substance:
0/Carbanilides; 0/Cesium Radioisotopes; 101-20-2/triclocarban; 3380-34-5/Triclosan; 7782-50-5/Chlorine
Comments/Corrections

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