Document Detail

Fate of nonreplaced sinuses of Valsalva in bicuspid aortic valve disease.
MedLine Citation:
PMID:  21036368     Owner:  NLM     Status:  In-Data-Review    
OBJECTIVE: There is growing consensus that the ascending aorta should be replaced at the time of aortic valve replacement for bicuspid aortic valve even if it is only moderately dilated; the natural history of nonreplaced sinuses of Valsalva is less clear.
METHODS: We identified patients without defined connective tissue disorder undergoing primary aortic valve replacement for bicuspid aortic valve and separate repair of the ascending aorta without root replacement at the Mayo Clinic between January 1, 1988, and December 31, 2007.
RESULTS: Among 218 patients, 65 underwent ascending aortoplasty and 153 underwent separate graft replacement of the ascending aorta. Of the latter group, 15 also had graft replacement of the noncoronary sinus. The mean age at operation was 62 ± 13 years. Valvular dysfunction was predominantly stenosis in 151 patients (70%), regurgitation in 54 patients (25%), and mixed in 12 patients (5%). At a follow-up of up to 17 years (median, 3.3 years; range, 0-17 years), 10 patients (5%) had undergone late reoperation, of whom 1 had replacement of the ascending aorta and 1 had replacement of the root for significant dilatation of the sinuses. Both patients had originally undergone aortoplasty. No other patient required root surgery. One-, 5-, and 10-year freedom from reoperation for any cause were 97.6%, 94.9%, and 85.5%, respectively.
CONCLUSIONS: Although progressive ascending aortic dilatation after aortic valve replacement for bicuspid aortic valve is well documented, progressive dilatation of nonreplaced sinuses is not evident. Separate valve and graft repair remains a reasonable surgical option in the setting of aortic valve replacement for bicuspid aortic valve with ascending aortic dilatation provided the sinuses of Valsalva are not significantly enlarged.
Chan B Park; Kevin L Greason; Rakesh M Suri; Hector I Michelena; Hartzell V Schaff; Thoralf M Sundt
Related Documents :
2142488 - Treatment of acute aortic dissection involving the right coronary artery and aortic valve.
10149108 - A new steerable cardiac catheter for crossing stenotic aortic valves.
14726058 - The congenitally bicuspid aortic valve: how does it function? why does it fail?
21047728 - Simulation of normal cardiovascular system and severe aortic stenosis using equivalent ...
7921378 - Treatment of internal mammary artery malperfusion syndrome by additional venous graft: ...
8901718 - Pharmacological control of pulmonary blood flow with inhaled nitric oxide after the fen...
Publication Detail:
Type:  Journal Article     Date:  2010-10-30
Journal Detail:
Title:  The Journal of thoracic and cardiovascular surgery     Volume:  142     ISSN:  1097-685X     ISO Abbreviation:  J. Thorac. Cardiovasc. Surg.     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-07-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0376343     Medline TA:  J Thorac Cardiovasc Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  278-84     Citation Subset:  AIM; IM    
Copyright Information:
Copyright © 2011 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.
Division of Cardiovascular Surgery, Mayo Clinic, Rochester, Minn; Department of Thoracic and Cardiovascular Surgery, St Paul's Hospital, The Catholic University of Korea, Seoul, Korea.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Superhydrophilic and antireflective La(OH)(3)/SiO(2)-nanorod/nanosphere films.
Next Document:  Less invasive versus conventional double-valve surgery: A propensity-matched comparison.