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Fate of aorta and clinical outcomes in patients with chronic type B aortic dissection: over 20-year experience.
MedLine Citation:
PMID:  23138605     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
AIM: In type B double-barrel aortic dissection (AD), the fate of the affected aorta, causes of death, and very long-term clinical outcomes have not been completely elucidated. The purpose of this study was to clarify the fate of the affected aorta and long-term clinical outcomes in patients with type B AD during the chronic phase. METHODS: One hundred four patients were entered into this study, and regular follow-up CT studies (mean; 87.6 months) were performed. Also, clinical data including AD-related events (including aneurysm formation, rupture, ischemia, and re-dissection), AD-related deaths, and long-term survival were retrospectively reviewed. RESULTS: Forty-six of 104 patients (44.2%) had one more AD-related event during the follow-up period. The actuarial event-free rates for any AD-related events of all patients were 95±2%, 75±5%, 53±6%, and 13±7% at 1, 5, 10, and 20 years, respectively. Initial aortic diameter ≥ 40 mm and blood flow in the false lumen were significant risk factors for AD-related events in univariate and multivariate analysis. CONCLUSION:In type B chronic aortic dissection, the affected aortas have a high incidence of AD-related events during the follow-up period. Prophylactic surgery or endovascular treatment for patients at high risk may reduce the AD-related events.
Authors:
E Sueyoshi; H Nagayama; T Hayashida; I Sakamoto; M Uetani
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-08
Journal Detail:
Title:  The Journal of cardiovascular surgery     Volume:  -     ISSN:  0021-9509     ISO Abbreviation:  J Cardiovasc Surg (Torino)     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-9     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0066127     Medline TA:  J Cardiovasc Surg (Torino)     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Radiology, Nagasaki University School of Medicine, 1-7-1 Sakamoto, Nagasaki, Japan - sueyo@nagasaki-u.ac.jp.
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