Document Detail


Fate of Friend leukaemia cells and lymphoma cells injected into mouse blastocysts.
MedLine Citation:
PMID:  6598575     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Our aim was to verify whether differentiated murine cells grafted into mouse blastocysts would follow the same fate as teratocarcinoma cells which lose their malignant character and participate in the development of the host embryo yielding chimaeric animals. Two combinations of host embryo-cancer cells were used. Animals were examined after birth or by pregnancy interruption at various stages of development. More than 350 animals obtained from cancer-cells-injected embryos failed to show direct evidence of loss of malignancy.
Authors:
E Calef; A Fruscalzo; R Jucker
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Cell differentiation     Volume:  15     ISSN:  0045-6039     ISO Abbreviation:  Cell Differ.     Publication Date:  1984 Dec 
Date Detail:
Created Date:  1985-07-29     Completed Date:  1985-07-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0342640     Medline TA:  Cell Differ     Country:  IRELAND    
Other Details:
Languages:  eng     Pagination:  181-4     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Blastocyst*
Cesarean Section
Chimera
Leukemia, Erythroblastic, Acute / pathology*
Lymphoma / pathology*
Male
Mice
Mice, Inbred C57BL
Mice, Inbred DBA
Mice, Inbred Strains
Neoplasm Transplantation

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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