Document Detail

Fate of Chlortetracycline in Korean Arable Soil.
MedLine Citation:
PMID:  21553029     Owner:  NLM     Status:  Publisher    
The widespread use of the pharmaceutical chlortetracycline to treat human and animal infectious diseases is raising concern in Korea regarding the potential development of antibiotic-resistant bacteria. This study investigated the fate of chlortetracycline in Korean arable soils, to assess its environmental impact. The estimated half-life of chlortetracycline was 26.70-27.17 days indoors and 18.63-30.16 days outdoors. The chlortetracycline epimers and metabolites, 4-epichlortetracycline and 4-epi-anydrochlotetracycline were determined using liquid chromatography tandem mass spectroscopy. The respective concentrations of 4-epi-anydrochlotetracycline and 4-epichlortetracycline were 1.91%-9.71% and 11.12%-23.92% of the total chlortetracycline residual concentration indoors and 2.96%-11.44% and 17.61%-40.73% outdoors.
Jin-Wook Kwon
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-5-7
Journal Detail:
Title:  Bulletin of environmental contamination and toxicology     Volume:  -     ISSN:  1432-0800     ISO Abbreviation:  -     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-5-9     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0046021     Medline TA:  Bull Environ Contam Toxicol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
National Veterinary Research & Quarantine Service (NVRQS), 620-2 Amnam-dong, Seo-gu, Busan, Republic of Korea,
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