| Fatal poisoning by vanadium. | |
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MedLine Citation:
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PMID: 21130588 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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We report here a fatal intoxication case involving ammonium vanadate. A 24-year-old woman was admitted to the Emergency Department for abdominal pain, nausea, vomiting, multiple daily diarrheas, hypoglycaemia (0.2g/L) and severe acute renal failure with glomerular filtration rate estimated at 21ml/min. This patient had taken an undetermined amount of ammonium vanadate 12h after ingesting. She died next morning in the context of respiratory distress despite intensive care and oxygen therapy. The autopsy revealed widespread asphyxia syndrome and erosive gastritis. Determination of vanadium concentration in blood was carried out by means of mass spectrometer (ICP-MS) using rhodium ((103)Rh) as the internal standard. The vanadium concentration was 6.22mg/L, corresponding to 6000 times higher than normal concentration in the general population. The latency and the brutality of clinical picture degradation seem to be in consideration of systemic poisoning by vanadium leading to inhibition of the cellular respiratory process. |
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Authors:
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Brahim Boulassel; Nouredine Sadeg; Olivier Roussel; Martine Perrin; Hafid Belhadj-Tahar |
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Publication Detail:
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Type: Journal Article Date: 2010-12-03 |
Journal Detail:
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Title: Forensic science international Volume: 206 ISSN: 1872-6283 ISO Abbreviation: Forensic Sci. Int. Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-03-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7902034 Medline TA: Forensic Sci Int Country: Ireland |
Other Details:
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Languages: eng Pagination: e79-81 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier Ireland Ltd. All rights reserved. |
Affiliation:
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Service Médecine Légale, CHU NEDIR Mohamed, Tizi-Ouzou, Algeria. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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