Document Detail


Fatal overdose of 2,4-dichlorophenoxyacetic acid (2,4-D).
MedLine Citation:
PMID:  8206450     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
An ingestion of an unknown quantity of U 46 D-Fluid (500 g dichlorophenoxyacetic acid/l) in a suicide is described. Although 2,4-dichlorophenoxyacetic acid (2,4 D) is widely used as a herbicide, intoxications are relatively rare. Quantitation of 2,4-D was performed by diethyl ether extraction from acidified samples (viscera) or by deproteinization (blood, plasma) with methanol before HPLC analysis. Postmortem concentrations of 2,4-D in body fluids and tissues are given. The proposed method resulted in a rapid procedure most useful in cases of deliberate poisoning with phenoxyacetic herbicides.
Authors:
T Keller; G Skopp; M Wu; R Aderjan
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Forensic science international     Volume:  65     ISSN:  0379-0738     ISO Abbreviation:  Forensic Sci. Int.     Publication Date:  1994 Mar 
Date Detail:
Created Date:  1994-07-11     Completed Date:  1994-07-11     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7902034     Medline TA:  Forensic Sci Int     Country:  IRELAND    
Other Details:
Languages:  eng     Pagination:  13-8     Citation Subset:  IM    
Affiliation:
Institute for Forensic Medicine, University of Heidelberg, Germany.
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MeSH Terms
Descriptor/Qualifier:
2,4-Dichlorophenoxyacetic Acid / analysis,  poisoning*
Body Fluids / chemistry
Chromatography, High Pressure Liquid
Fatal Outcome
Humans
Male
Middle Aged
Multiple Organ Failure / chemically induced
Overdose
Postmortem Changes
Sensitivity and Specificity
Suicide*
Chemical
Reg. No./Substance:
94-75-7/2,4-Dichlorophenoxyacetic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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