Document Detail


Fatal neonatal parechovirus encephalitis.
MedLine Citation:
PMID:  22171236     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Two infants developed encephalitis in the late neonatal period due to human parechovirus type 3 (HPeV-3). This finally resulted in intractable seizures leading to death. Both presented with classical signs and symptoms. HPeV-3 was detected in nasopharyngeal and rectal swabs, cerebrospinal fluid, serum and postmortem samples (for one infant). Ultrasound and magnetic resonance imaging findings showed severe white matter injury in one infant, and limited hippocampal injury in the other. Parents consented to autopsy in the latter, showing diffuse gliotic oedema of cerebral white matter, bilateral bronchopneumonia, and inflammation in spleen. We emphasise that polymerase chain reaction (PCR) testing for parechovirus in neonates with severe sepsis-like syndrome and meningoencephalitis is mandatory.
Authors:
Arjen L van Zwol; Maarten Lequin; Coranne Aarts-Tesselaar; Annemiek A van der Eijk; Gertjan A Driessen; Matthijs de Hoog; Paul Govaert
Related Documents :
8835246 - Persistence of enthesopathic changes in patients with spondylarthropathy during a 6-mon...
3627196 - Sickle-cell trait as a risk factor for sudden death in physical training.
10592476 - Achondroplasia and cervicomedullary compression: prospective evaluation and surgical tr...
16877386 - Characterization of rhodopsin p23h-induced retinal degeneration in a xenopus laevis mod...
16283946 - Case-control study of sudden infant death syndrome in lithuania, 1997-2000.
9974496 - Transcranial doppler in the newborn with asphyxia.
Publication Detail:
Type:  Journal Article     Date:  2009-12-14
Journal Detail:
Title:  BMJ case reports     Volume:  2009     ISSN:  1757-790X     ISO Abbreviation:  BMJ Case Rep     Publication Date:  2009  
Date Detail:
Created Date:  2011-12-15     Completed Date:  2012-10-02     Revised Date:  2013-04-02    
Medline Journal Info:
Nlm Unique ID:  101526291     Medline TA:  BMJ Case Rep     Country:  England    
Other Details:
Languages:  eng     Pagination:  -     Citation Subset:  -    
Affiliation:
Erasmus Medical Centre, Sophia Children's Hospital, Neonatology, Dr Molewaterplein 60, 3015 GJ Rotterdam, Rotterdam, 3015GJ, Netherlands.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Mental illness that is difficult to classify: a case study.
Next Document:  An asymptomatic presentation of gastric outlet obstruction secondary to congenital antral web in an ...