Document Detail


Fatal nefopam overdose.
MedLine Citation:
PMID:  20360495     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Nefopam hydrochloride (Acupan) is a potent non-opioid analgesic widely used for the relief of moderate to severe postoperative pain. The drug is generally well tolerated, but it has a broad spectrum of side effects including tachycardia, sweating, nausea, seizures and hallucinations. When taken in overdose, nefopam has been reported to cause cardiac conduction abnormalities, cerebral oedema, fever and renal failure. The case is presented of a previously healthy 19-year-old man who presented to the emergency department in cardiac arrest following intentional nefopam overdose. It is only the fourth reported case of fatal nefopam overdose in the literature.
Authors:
Deborah E Kerr; Alan K Fletcher
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Publication Detail:
Type:  Journal Article     Date:  2010-04-01
Journal Detail:
Title:  Emergency medicine journal : EMJ     Volume:  27     ISSN:  1472-0213     ISO Abbreviation:  Emerg Med J     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-05-05     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100963089     Medline TA:  Emerg Med J     Country:  England    
Other Details:
Languages:  eng     Pagination:  407-8     Citation Subset:  IM    
Affiliation:
Emergency Department, Northern General Hospital, Sheffield, UK. debbiekerr@doctors.org.uk
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