Document Detail

Fatal migraine.
MedLine Citation:
PMID:  6568948     Owner:  NLM     Status:  MEDLINE    
A 58-year-old woman, with a past history of classic migraine since youth, suddenly experienced blurred vision and flexor spasms of her left hand, followed by a right hemicrania and photophobia, similar to previous attacks of migraine. Within a few hours a progressive left hemiplegia and paralysis of left conjugate gaze developed. Severe right hemicrania continued. CT brain scans showed a progressing large right parietotemporal infarct. Her level of consciousness declined and she died ten days after admission to hospital. The autopsy showed a large infarct in the area of supply of the right middle cerebral artery, associated with oedema and with a shift of midline structures to the left, with cingulate and right hippocampal herniation. There was secondary midbrain haemorrhage. Recent secondary haemorrhagic infarction was present in the left calcarine cortex. The carotid arteries in the neck showed only minimal atheromatous change and were patent; the cerebral arteries were remarkably free of atheroma, but the right middle cerebral artery contained red thrombus. Histologically the cerebral infarction antedated the middle cerebral artery thrombus by several days, supporting arterial spasm as the cause of infarction. The thrombosis was considered to be a secondary phenomenon.
G Selby; J A Fryer
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Clinical and experimental neurology     Volume:  20     ISSN:  0196-6383     ISO Abbreviation:  Clin Exp Neurol     Publication Date:  1984  
Date Detail:
Created Date:  1985-02-20     Completed Date:  1985-02-20     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  7909724     Medline TA:  Clin Exp Neurol     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  85-92     Citation Subset:  IM    
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MeSH Terms
Brain / pathology*
Cerebral Infarction / diagnosis,  etiology*,  pathology
Middle Aged
Migraine Disorders / complications*,  mortality,  pathology
Tomography, X-Ray Computed

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