Document Detail


FATAL LIVER DAMAGE AFTER BARIUM ENEMAS CONTAINING TANNIC ACID.
MedLine Citation:
PMID:  14079135     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Tannic acid contained in the barium enema was found to have been the sole known potential hepatotoxin in four of the five cases of fulminating fatal liver failure that occurred in a 213-bed hospital over a period of 27 months. In the other case halothane anesthesia had also been administered. Autopsies (performed on four of the cases) did not suggest viral hepatitis but showed substantially indentical hepatic changes, not unlike those reported in the past following tannic acid exposure. Proof is not claimed that tannic acid was the cause of these deaths, but further investigation regarding the safety of its administration in barium enemas is advocated.
Authors:
H H LUCKE; K E HODGE; N L PATT
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Canadian Medical Association journal     Volume:  89     ISSN:  0008-4409     ISO Abbreviation:  Can Med Assoc J     Publication Date:  1963 Nov 
Date Detail:
Created Date:  1964-03-01     Completed Date:  1996-12-01     Revised Date:  2011-09-28    
Medline Journal Info:
Nlm Unique ID:  0414110     Medline TA:  Can Med Assoc J     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  1111-4     Citation Subset:  OM    
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MeSH Terms
Descriptor/Qualifier:
Barium Sulfate*
Drug-Induced Liver Injury*
Enema*
Tannins*
Toxicology*
Chemical
Reg. No./Substance:
0/Tannins; 7727-43-7/Barium Sulfate
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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