Document Detail

Fatal and life threatening rupture of splenic artery aneurysms in children with portal hypertension.
MedLine Citation:
PMID:  15049802     Owner:  NLM     Status:  MEDLINE    
Aneurysms of the splenic artery (SAAs) are a rare complication of portal hypertension in adults. Although the risk of rupture is small, associated mortality is high. Furthermore, circulatory changes that occur following liver transplantation (OLT) may increase the risk of SAA rupture. The incidence in children with portal hypertension is unknown and thus we present our experience with two children who had ruptured SAA, one of whom died. Although there are no accepted methods for routine screening, hepatic angiography should be considered in children with long-standing portal hypertension (more than 10 yr), in order to detect and consider resection of the aneurysms, either before or at the time of liver transplantation.
Helen M Evans; Khalid Sharif; Rachel M Brown; Craig Platt; William J Crisp; Deirdre A Kelly
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric transplantation     Volume:  8     ISSN:  1397-3142     ISO Abbreviation:  Pediatr Transplant     Publication Date:  2004 Apr 
Date Detail:
Created Date:  2004-03-30     Completed Date:  2004-07-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9802574     Medline TA:  Pediatr Transplant     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  192-5     Citation Subset:  IM    
Copyright Information:
Copyright 2004 Blackwell Munksgaard
The Liver Unit, Birmingham Children's Hospital, Birmingham, UK.
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MeSH Terms
Aneurysm, Ruptured / etiology*
Fatal Outcome
Graft Survival
Hematoma / etiology
Hypertension, Portal / complications*
Liver Transplantation / adverse effects
Portoenterostomy, Hepatic / adverse effects
Postoperative Hemorrhage / etiology
Rupture, Spontaneous
Splenic Artery / pathology*

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