Document Detail


Fatal leaflet escape in an Edwards TEKNA aortic prosthesis.
MedLine Citation:
PMID:  16480019     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The case is reported of a 26-year-old male patient who died eight years after the replacement of an aortic valve with a bileaflet mechanical valve (TEKNA; Edwards, USA). Following prosthesis implantation, the patient had been in a good state of health, and his death occurred unexpectedly. Forensic autopsy revealed a leaflet escape, with two fragments of the leaflet being found bilaterally in the common iliac arteries. Death occurred due to an acute cardiac insufficiency. Immunohistochemical investigations revealed fresh myocardial fiber necroses. Stereomicroscopic and scanning electron microscopic investigations demonstrated surface erosions of the leaflet. Although the valve was withdrawn from the market in June 2000, it had previously been implanted in over 18,000 patients. Thus, from a clinical viewpoint, the question of using a prophylactic replacement in affected patients must be discussed.
Authors:
Heidi Pfeiffer; Julia Bertolini; Hans Heinrich Scheld; Bernd Brinkmann
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of heart valve disease     Volume:  15     ISSN:  0966-8519     ISO Abbreviation:  J. Heart Valve Dis.     Publication Date:  2006 Jan 
Date Detail:
Created Date:  2006-02-16     Completed Date:  2006-09-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9312096     Medline TA:  J Heart Valve Dis     Country:  England    
Other Details:
Languages:  eng     Pagination:  97-9     Citation Subset:  IM    
Affiliation:
Institute of Legal Medicine, University Hospital Münster, Münster, Germany. pfeiffh@uni-muenster.de
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MeSH Terms
Descriptor/Qualifier:
Adult
Aortic Valve Stenosis / congenital,  surgery*
Autopsy
Embolism / etiology
Fatal Outcome
Foreign-Body Migration / complications*,  etiology
Heart Valve Prosthesis / adverse effects*
Heart Valve Prosthesis Implantation / adverse effects
Humans
Iliac Artery / pathology
Male
Myocardium / pathology
Necrosis / etiology
Prosthesis Failure

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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