Document Detail


Fatal intoxication with omethoate.
MedLine Citation:
PMID:  12185494     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A case of suicide with the insecticide omethoate is reported. An 18-year-old apprentice gardener had ingested an unknown amount of omethoate. His body was found in his room lying in the storage space under his bed. The autopsy first showed multiple superficial incisions in the skin of his wrists, furthermore hemorrhagic pulmonary oedema, dilation of the right cardiac ventricle and oedema of the brain. The gastric mucosa was swollen and showed a dark brownish colour. An intensive, chemical-like smell rose from the corpse and organs. Toxicological analysis detected omethoate in cardiac blood (208 micro g/ml), urine (225 micro g/ml) and bile (524 micro g/ml), in the liver (341 micro g/ml) and kidneys (505 micro g/ml). In the gastric content the level was 48223 micro g/ml. The amount of the active AChE in peripheral blood serum was reduced to less than 0.2% of the normal level. To our knowledge no case of a fatal suicide by ingestion of omethoate has been reported in literature.
Authors:
M Pavlic; A Haidekker; P Grubwieser; W Rabl
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2002-04-17
Journal Detail:
Title:  International journal of legal medicine     Volume:  116     ISSN:  0937-9827     ISO Abbreviation:  Int. J. Legal Med.     Publication Date:  2002 Aug 
Date Detail:
Created Date:  2002-08-19     Completed Date:  2003-02-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9101456     Medline TA:  Int J Legal Med     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  238-41     Citation Subset:  IM    
Affiliation:
Institute of Legal Medicine, Leopold-Franzens-University of Innsbruck, Muellerstrasse 44, 6020 Innsbruck. marion.pavlic@uibk.ac.at
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MeSH Terms
Descriptor/Qualifier:
Acetylcholinesterase / blood
Adolescent
Austria
Autopsy
Cholinesterase Inhibitors / analysis,  pharmacokinetics,  poisoning*
Chromatography, Gas
Dimethoate / analogs & derivatives*,  analysis,  pharmacokinetics,  poisoning*
Fatal Outcome
Humans
Insecticides / analysis,  pharmacokinetics,  poisoning*
Male
Poisoning / blood
Suicide
Tissue Distribution
Chemical
Reg. No./Substance:
0/Cholinesterase Inhibitors; 0/Insecticides; 1113-02-6/dimethoxon; 60-51-5/Dimethoate; EC 3.1.1.7/Acetylcholinesterase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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