| Fatal interstitial pneumonitis in a patient with relapsed diffuse large B cell lymphoma following yttrium-90 ibritumomab tiuxetan. | |
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MedLine Citation:
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PMID: 20490611 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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There is no previous report of fatal interstitial pneumonitis related to the administration of yttirum-90 ibritumomab tiuxetan. We report first case of fatal interstitial pneumonitis in a 35-year-old female patient with relapsed diffuse large B cell lymphoma following yttrium-90 ibritumomab tiuxetan. A pathological evaluation through a surgical lung biopsy demonstrated a "interstitial pneumonitis" pattern. Although high-dose methylprednisolone was administered, she died due to acute respiratory distress syndrome, secondary to radioimmunotherapy-induced interstitial pneumonitis. In this report, we discuss the etiology, diagnosis, and management of radioimmunotherapy-induced interstitial pneumonitis. |
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Authors:
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Moon Jin Kim; Gyeong-Won Lee; Jong Woo Seo; Hyun-Jung Kim; Sung-Nam Lim; Cheolwon Suh |
Publication Detail:
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Type: Journal Article Date: 2010-05-21 |
Journal Detail:
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Title: Investigational new drugs Volume: 29 ISSN: 1573-0646 ISO Abbreviation: Invest New Drugs Publication Date: 2011 Oct |
Date Detail:
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Created Date: 2011-08-24 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8309330 Medline TA: Invest New Drugs Country: United States |
Other Details:
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Languages: eng Pagination: 1098-101 Citation Subset: IM |
Affiliation:
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Department of Internal Medicine, School of Medicine, Gyeongsang National University, Jinju, Republic of Korea. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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