| Fatal hypothermia related vacuolation of hormone-producing cells in the anterior pituitary. | |
| | |
MedLine Citation:
|
PMID: 15231284 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
We found small cytoplasmic vacuoles in the hormone-producing cells of anterior pituitary in hypothermic death. The vacuoles were found in approximately 40% of anterior pituitary cells both in males and females that had died from cold (n=31) while the detection rate was lower than 1% (P <0.001) in the other causes of death (n=180: fire death, n=25; fatal injury, n=24; asphyxia, n=24; poisoning, n=8; natural diseases, n=103). The detection rate in hypothermic death was the highest in ACTH cells (about 65%), followed by gonadotrophs (about 43%), and the lowest in TSH cells (about 16%) (P <0.001). These findings suggest that the cytoplasmic vacuoles in the anterior pituitary cells may be the most closely related to cold exposure among the above-mentioned cause of death, providing a supplementary evidence for determining the causes of death. |
| | |
Authors:
|
T Ishikawa; S Miyaishi; T Tachibana; H Ishizu; B-L Zhu; H Maeda |
Related Documents
:
|
8046294 - Functional heterogeneity with respect to oestrogen treatment in prolactin cell subpopul... 7756734 - In vitro modifications in the proliferation rate of prolactin cells are accompanied by ... 3607854 - The relation between pituitary gland and thyroid growth during the lifespan of the annu... 2997234 - Secretory protein targeting in a pituitary cell line: differential transport of foreign... 2298254 - Effects of leptomycin b on the cell cycle of fibroblasts and fission yeast cells. 23583584 - Socs36e attenuates stat signaling to optimize motile cell specification in the drosophi... |
Publication Detail:
|
Type: Comparative Study; Journal Article |
Journal Detail:
|
Title: Legal medicine (Tokyo, Japan) Volume: 6 ISSN: 1344-6223 ISO Abbreviation: Leg Med (Tokyo) Publication Date: 2004 Jul |
Date Detail:
|
Created Date: 2004-07-02 Completed Date: 2005-01-11 Revised Date: 2008-11-21 |
Medline Journal Info:
|
Nlm Unique ID: 100889186 Medline TA: Leg Med (Tokyo) Country: Ireland |
Other Details:
|
Languages: eng Pagination: 157-63 Citation Subset: IM |
Affiliation:
|
Department of Legal Medicine, Osaka City University Medical School, Asahi-machi 1-4-3, Abeno, Osaka 545-8558, Japan. takaki@med.osaka-cu.ac.jp |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adrenocorticotropic Hormone
/
metabolism Adult Aged Asphyxia / mortality, pathology Cold Temperature Female Humans Hypothermia / mortality*, pathology* Male Microscopy, Electron Middle Aged Pituitary Gland, Anterior / metabolism, pathology*, ultrastructure Pituitary Hormones, Anterior / metabolism* Poisoning / mortality, pathology Thyrotropin / metabolism Vacuoles / pathology* Wounds and Injuries / mortality, pathology |
| Chemical | |
Reg. No./Substance:
|
0/Pituitary Hormones, Anterior; 9002-60-2/Adrenocorticotropic Hormone; 9002-71-5/Thyrotropin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Victimiologic study of female homicide.
Next Document: Nicotine and cotinine levels in blood and urine from forensic autopsy cases.