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Fatal human monocytic ehrlichiosis: a case study.
MedLine Citation:
PMID:  21279705     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Human ehrlichiosis is the term for a collection of tick-borne diseases caused primarily by obligate intracellular bacteria of the Ehrlichia species. Ehrlichiosis is characterized by a mild to severe illness, with approximately 3-5% of cases proving fatal despite receiving appropriate care. This report presents the case of a 60 year-old woman who was found collapsed and unresponsive in her home after an indeterminate time; possibly for up to 48 h. Despite rigorous resuscitative care and antibiotic treatment, the patient lapsed into multi-organ failure and died. Subsequent analysis by microscopic examination, PCR and immunohistochemistry revealed the patient died from an infection of Ehrlichia chaffeensis. Clinicians and pathologists must be aware of this emergent disease in order to make a timely and appropriate diagnosis. Discussion of the patient's clinical, laboratory and autopsy findings as well as treatment of Ehrlichia chaffeensis infections is presented.
Authors:
Joseph J Pavelites; Joseph A Prahlow
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-1-30
Journal Detail:
Title:  Forensic science, medicine, and pathology     Volume:  -     ISSN:  1556-2891     ISO Abbreviation:  -     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-1-31     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101236111     Medline TA:  Forensic Sci Med Pathol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Transitional Year Program, GME Office, Dwight D. Eisenhower Army Medical Center, Building 300, Hospital Road, Ft. Gordon, GA, 30905, USA, joseph.pavelites@amedd.army.mil.
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