Document Detail

Fatal hemorrhage following trans--sphenoidal resection of a pituitary adenoma: a case report and review of the literature.
MedLine Citation:
PMID:  20306333     Owner:  NLM     Status:  MEDLINE    
A 58-year-old woman with acromegaly developed massive epistaxis 7 days following trans-sphenoidal resection of a growth hormone-secreting pituitary adenoma. At autopsy, it was determined that the source of the hemorrhage was a rupture of the intracavernous segment of the internal carotid artery secondary to a bacterial arteritis. We describe the gross dissection and histologic examination undertaken in this unusual case, discuss the possible etiology of the infection and review the potential complications of this surgical approach with a view to improving forensic examination of these patients.
C Kepron; M Cusimano; M S Pollanen
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Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2010-03-21
Journal Detail:
Title:  Forensic science, medicine, and pathology     Volume:  6     ISSN:  1556-2891     ISO Abbreviation:  Forensic Sci Med Pathol     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-09-16     Completed Date:  2011-01-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101236111     Medline TA:  Forensic Sci Med Pathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  282-7     Citation Subset:  IM    
Department of Laboratory Medicine and Pathobiology, University of Toronto, Medical Sciences Building, Room 6215, 1 King's College Circle, Toronto, ON M5S 1A8, Canada.
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MeSH Terms
Adenoma / pathology,  surgery*
Arteritis / etiology*,  microbiology
Carotid Artery, Internal / microbiology,  pathology,  surgery*
Epistaxis / etiology*
Fatal Outcome
Growth Hormone-Secreting Pituitary Adenoma / pathology,  surgery*
Heart Arrest / etiology
Middle Aged
Neoplasm Invasiveness
Neurosurgical Procedures / adverse effects*
Postoperative Hemorrhage / etiology*
Rupture, Spontaneous
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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