Document Detail


Fatal haemorrhagic chickenpox complicating nephrotic syndrome.
MedLine Citation:
PMID:  8183171     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report a 14 year old Indian-Muslim girl who developed a fulminant, disseminated and fatal varicella infection while receiving steroids for nephrotic syndrome. The terminal phase of her illness was complicated by a bleeding dyscrasia and circulatory collapse. Varicella infection in healthy children is a benign disease. However in neonates and immunosuppressed patients it may be severe and often fatal. There are many reports of fatalities occurring in cancer patients receiving chemotherapy, patients on immunosuppressives for asthma, haemolytic anaemia, rheumatic fever, and renal and bone marrow transplantation. Patients with nephrotic syndrome receiving cyclophosphamide treatment are at particular risk of developing severe chickenpox infection. To our knowledge, there has been only one report of fatal chickenpox infection in a child who received steroids for nephrotic syndrome. We report here a case of fatal haemorrhagic chickenpox complicating nephrotic syndrome.
Authors:
H B Gangaram; I K Cheong
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Medical journal of Malaysia     Volume:  48     ISSN:  0300-5283     ISO Abbreviation:  Med. J. Malaysia     Publication Date:  1993 Dec 
Date Detail:
Created Date:  1994-06-14     Completed Date:  1994-06-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0361547     Medline TA:  Med J Malaysia     Country:  MALAYSIA    
Other Details:
Languages:  eng     Pagination:  446-8     Citation Subset:  IM    
Affiliation:
Department of Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Chickenpox / etiology*
Fatal Outcome
Female
Hemorrhage / etiology*
Humans
Nephrotic Syndrome / complications*,  drug therapy
Prednisolone / adverse effects
Chemical
Reg. No./Substance:
50-24-8/Prednisolone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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