Document Detail

Fatal disseminated Acremonium strictum infection in a preterm newborn: a very rare cause of neonatal septicaemia.
MedLine Citation:
PMID:  12909663     Owner:  NLM     Status:  MEDLINE    
Species of the genus Acremonium (Cephalosporium) are opportunistic micro-organisms that are environmentally widespread saprophytes in soil and can, very rarely, be pathogenic in humans. Disseminated infection has been described in patients with immunodeficiency, but has previously been reported in only one neonate. A preterm infant with Acremonium strictum fungaemia is reported here. The patient was born at 27 weeks gestation and weighed 870 g at birth. She needed intensive respiratory management and became septic on day 11 of life. Blood and cerebrospinal fluid (CSF) cultures were positive for A. strictum. The patient did not respond to therapy with amphotericin B plus fluconazole and died on day 25 of life. The autopsy showed foci due to A. strictum in the brain, liver and heart.
Mehmet Yalaz; Suleyha Hilmioglu; Dilek Metin; Mete Akisu; Deniz Nart; Hasan Cetin; Cengiz Ozturk; Ecmel Isik; Nilgun Kultursay
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of medical microbiology     Volume:  52     ISSN:  0022-2615     ISO Abbreviation:  J. Med. Microbiol.     Publication Date:  2003 Sep 
Date Detail:
Created Date:  2003-08-11     Completed Date:  2003-10-09     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0224131     Medline TA:  J Med Microbiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  835-7     Citation Subset:  IM    
Division of Neonatology, Department of Pediatrics, Ege University Faculty of Medicine, Izmir, Turkey.
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MeSH Terms
Acremonium / isolation & purification*
Fatal Outcome
Fungemia / microbiology*
Infant, Newborn
Infant, Premature*
Mycoses / microbiology*

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