Document Detail


Fatal cytauxzoonosis in captive-reared lions in Brazil.
MedLine Citation:
PMID:  17306459     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Fatal cytauxzoonosis is described in a captive reared lioness (Panthera leo) and its 6-month-old cub. Clinical signs in the lioness included loss of weight, depression, anaemia, loss of hair, dark discolored urine, tachypnoea, nystagmus, deaphness and staggering gait. The cub died after a short period of depression. In the lioness, laboratory examination revealed normochromic normocytic anaemia, neutrophilia, lymphopenia, monocytosis, eosinopenia, thrombocytopenia, proteinuria, pyuria, haematuria and increased. At necropsy the lioness showed marked pulmonary edema and slight gelatinous translucent edema in the mediastinum, petechiae and echymosis disseminated in the serosae, and the intestinal content was red and semiliquid. The cub presented hemothorax, endocardial and pulmonary edema, petechiae in the cardiac serosae, hepatic and splenic congestion and segments of the small intestine with blood stained fluid contents and reddish mesenteric lymph nodes. Histopathological examination of liver, spleen, heart, lungs, intestines, pancreas, mesenteric lymph nodes, kidneys, skeletal muscle, brain and skin revealed large number of intravascular macrophages with their cytoplasm filled with various schizogonic stages of a Theileriidae. Electron microscopy confirmed the presence of schizonts in endothelial-associated macrophages. The diagnosis was established by the finding of the pathognomonic schizonts in macrophages within blood vessels in several organs and tissues from both lions. This is the first report of feline cytauxzoonosis in P. leo and of a confirmed infection by Cytauxzoon felis in felidae in South America.
Authors:
P V Peixoto; C O Soares; A Scofield; C D Santiago; T N França; S S Barros
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't     Date:  2007-02-15
Journal Detail:
Title:  Veterinary parasitology     Volume:  145     ISSN:  0304-4017     ISO Abbreviation:  Vet. Parasitol.     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-03-26     Completed Date:  2007-11-05     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  7602745     Medline TA:  Vet Parasitol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  383-7     Citation Subset:  IM    
Affiliation:
Departamento de Nutrição Animal e Pastagem, Instituto de Zootecnia, Universidade Federal Rural do Rio de Janeiro, Km 47, 23890-000 Seropédica, RJ, Brazil. pfpeixoto@terra.com.br
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MeSH Terms
Descriptor/Qualifier:
Animals
Animals, Zoo / parasitology*
Brazil / epidemiology
Eukaryota / classification,  isolation & purification
Female
Lions / parasitology*
Protozoan Infections, Animal / epidemiology,  parasitology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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