| Fatal TRALI associated with neutrophil antibodies in a recipient of pre-storage leukocyte-reduced blood components. | |
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MedLine Citation:
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PMID: 19687592 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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A 53-year-old man developed possible transfusion-related acute lung injury (TRALI) after red cell component transfusion. The patient developed autoimmune neutropenia with the expression of neutrophil antibodies. Neutrophil aggregation, endothelial damage, and development of a large thrombus containing platelets were observed post mortem in his pulmonary vessels. The patient also had subacute organizing pneumonia. He received blood components treated with universal pre-storage leuko-reduction. Even though leukocytes in the blood components are reduced to a few million by this process, TRALI can be fatal, as was the case for this recipient, who had subacute organizing pneumonia in conjunction with immune-mediated neutropenia. |
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Authors:
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Kazuyoshi Ishii; Eiji Kadota; Michiomi Shimizu; Shosaku Nomura |
Publication Detail:
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Type: Case Reports; Journal Article Date: 2009-08-17 |
Journal Detail:
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Title: Internal medicine (Tokyo, Japan) Volume: 48 ISSN: 1349-7235 ISO Abbreviation: Intern. Med. Publication Date: 2009 |
Date Detail:
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Created Date: 2009-08-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9204241 Medline TA: Intern Med Country: Japan |
Other Details:
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Languages: eng Pagination: 1429-31 Citation Subset: IM |
Affiliation:
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Department of Hematology, Kishiwada City Hospital, Osaka. ishiikaz@silver.ocn.ne.jp |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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