| Fatal massive hemoptysis in a patient on low-dose oral prednisone: chronic necrotizing pulmonary aspergillosis. | |
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MedLine Citation:
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PMID: 17319045 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report a case of chronic necrotizing aspergillosis in a 74-year-old man with chronic lung disease, who was on low-dose prednisone. The patient was treated with various antibiotics but had no improvement. Sample obtained via bronchoscopy grew Aspergillus, and the patient was started on lipid formulation amphotericin B. Three days after admission the patient developed fatal massive hemoptysis, presumably secondary to acquired systemic-to-pulmonary vascular communication. This is an unusual presentation of a rare manifestation of pulmonary aspergillosis. A high index of suspicion is needed to diagnose this susceptible patients. |
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Authors:
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Bobbak Vahid; Paul Marik |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Respiratory care Volume: 52 ISSN: 0020-1324 ISO Abbreviation: Respir Care Publication Date: 2007 Jan |
Date Detail:
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Created Date: 2007-02-23 Completed Date: 2007-03-20 Revised Date: 2008-02-19 |
Medline Journal Info:
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Nlm Unique ID: 7510357 Medline TA: Respir Care Country: United States |
Other Details:
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Languages: eng Pagination: 56-8 Citation Subset: IM |
Affiliation:
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Department of Pulmonary and Critical Care Medicine, Thomas Jefferson University, Philadelphia, PA 19107, USA. bobbak.vahid@mail.tju.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Aspergillosis, Allergic Bronchopulmonary* / complications, drug therapy, pathology Aspergillus fumigatus / isolation & purification Chronic Disease Fatal Outcome Glucocorticoids / administration & dosage*, therapeutic use Hemoptysis / diagnosis, etiology* Humans Lung / microbiology, pathology, radiography Male Necrosis Prednisone / administration & dosage*, therapeutic use Severity of Illness Index Tomography, X-Ray Computed |
| Chemical | |
Reg. No./Substance:
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0/Glucocorticoids; 53-03-2/Prednisone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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