Document Detail

Fatal Clostridium perfringens septicemia associated with gastrointestinal arteriovenous malformations (vascular ectasias).
MedLine Citation:
PMID:  2540727     Owner:  NLM     Status:  MEDLINE    
Clostridial infections usually occur in association with trauma, malignancy, or intra-abdominal disease. A 72-year-old previously healthy man presented with abdominal distress and fever. He developed a hemolytic anemia, coagulopathy, and fulminant clostridial septicemia. The patient died less than 24 hours after presentation. At autopsy, no malignancy was detected. The patient had an acute clostridial hepatic abscess and multiple arteriovenous malformations (vascular ectasias) of the large and small bowel. The case suggests that these mucosal and submucosal vascular lesions, which usually cause hemorrhage, may also predispose to infection.
C M Craven
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Archives of pathology & laboratory medicine     Volume:  113     ISSN:  0003-9985     ISO Abbreviation:  Arch. Pathol. Lab. Med.     Publication Date:  1989 May 
Date Detail:
Created Date:  1989-06-02     Completed Date:  1989-06-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7607091     Medline TA:  Arch Pathol Lab Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  534-5     Citation Subset:  AIM; IM    
Department of Pathology, University of Utah, Salt Lake City 84132.
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MeSH Terms
Arteries / abnormalities
Arteriovenous Malformations / complications*,  pathology
Clostridium Infections / complications*,  pathology
Clostridium perfringens / isolation & purification
Digestive System / blood supply*,  pathology
Sepsis / complications*,  mortality,  pathology
Veins / abnormalities

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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