Document Detail


Fatal cerebral phaeohyphomycosis in an immunocompetent individual due to Thielavia subthermophila.
MedLine Citation:
PMID:  21411574     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report the first case of fatal brain infection in an Indian farmer caused by Thielavia subthermophila, a dematiaceous thermophilic fungus in the order Sordariales, and present a review of previous infections from this order. The patient failed amphotericin B therapy combined with surgical excision despite the drug's low MICs in vitro.
Authors:
Hamid Badali; Jagdish Chander; Ashish Gupta; Hena Rani; Rajpal Singh Punia; G Sybren De Hoog; Jacques F Meis
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't     Date:  2011-03-16
Journal Detail:
Title:  Journal of clinical microbiology     Volume:  49     ISSN:  1098-660X     ISO Abbreviation:  J. Clin. Microbiol.     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-05-27     Completed Date:  2011-08-17     Revised Date:  2013-06-30    
Medline Journal Info:
Nlm Unique ID:  7505564     Medline TA:  J Clin Microbiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2336-41     Citation Subset:  IM    
Affiliation:
Department of Medical Mycology and Parasitology, School of Medicine/Molecular and Cell Biology Research Centre, Mazandaran University of Medical Sciences, Sari, Iran.
Data Bank Information
Bank Name/Acc. No.:
GENBANK/HM448441;  HM448442
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MeSH Terms
Descriptor/Qualifier:
Adult
Amphotericin B / administration & dosage,  pharmacology
Antifungal Agents / administration & dosage,  pharmacology
Brain / microbiology,  pathology*
Central Nervous System Fungal Infections / complications,  diagnosis*,  pathology*,  therapy
DNA, Fungal / chemistry,  genetics
DNA, Ribosomal Spacer / chemistry,  genetics
Debridement
Fatal Outcome
Humans
India
Male
Microbial Sensitivity Tests
Molecular Sequence Data
Phylogeny
Sequence Analysis, DNA
Sordariales / isolation & purification*
Chemical
Reg. No./Substance:
0/Antifungal Agents; 0/DNA, Fungal; 0/DNA, Ribosomal Spacer; 1397-89-3/Amphotericin B
Comments/Corrections

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