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Fatal Acute Pancreatitis Associated with Reactive AA Amyloidosis in Rheumatoid Arthritis with End-stage Renal Disease: A Report of Three Cases.
MedLine Citation:
PMID:  21467708     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
We report three cases of fatal pancreatitis associated with systemic AA amyloidosis in rheumatoid arthritis (RA). All of the patients showed end-stage renal failure, and hemodialysis was introduced during the course of treatment. Autopsy was performed on two of the three patients, and this revealed amyloid deposition on the vascular walls in the pancreas. It was strongly suggested that the acute pancreatitis in all three patients was attributable to deposition of amyloid in vascular and pancreatic tissues. Acute pancreatitis is considered to be a rare complication of end-stage amyloidosis associated with RA, and is frequently fatal. It is important to treat RA patients intensively to avoid such deposition of amyloid.
Authors:
Takeshi Kuroda; Hiroe Sato; Hisashi Hasegawa; Yoko Wada; Shuichi Murakami; Takako Saeki; Masaaki Nakano; Ichiei Narita
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Publication Detail:
Type:  Journal Article     Date:  2011-04-01
Journal Detail:
Title:  Internal medicine (Tokyo, Japan)     Volume:  50     ISSN:  1349-7235     ISO Abbreviation:  Intern. Med.     Publication Date:  2011  
Date Detail:
Created Date:  2011-04-06     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9204241     Medline TA:  Intern Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  739-44     Citation Subset:  IM    
Affiliation:
Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Japan.
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