Document Detail

Fat-supplemented diet protects against activity-stress ulcers in rats.
MedLine Citation:
PMID:  6617808     Owner:  NLM     Status:  MEDLINE    
Rats were exposed to a fat-supplemented (32.5% beef tallow) diet from weaning until they were 200 g in weight. Half the animals were exposed to the activity stress paradigm consisting of housing in standard activity-wheel cages while restricting their food intake to 1 h each day. Control rats were treated in the same fashion but on a fat-free (0.08%) diet. Fat-supplemented activity-stressed rats exhibited high levels of running wheel activity but less mortality and less gastric pathology than fat-free controls which were exposed to the activity-stress procedure. Ulcers were not observed in home cage housed rats in either diet condition.
G B Glavin
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Experientia     Volume:  39     ISSN:  0014-4754     ISO Abbreviation:  Experientia     Publication Date:  1983 Oct 
Date Detail:
Created Date:  1983-11-23     Completed Date:  1983-11-23     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0376547     Medline TA:  Experientia     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  1097-9     Citation Subset:  IM    
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MeSH Terms
Dietary Fats / administration & dosage,  therapeutic use*
Peptic Ulcer / etiology,  prevention & control*
Physical Exertion
Rats, Inbred Strains
Stress, Physiological / complications*
Reg. No./Substance:
0/Dietary Fats

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