Document Detail


Fat oxidation and its relation to serum parathyroid hormone in young women enrolled in a 1-y dairy calcium intervention.
MedLine Citation:
PMID:  16332655     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Increased dietary calcium is associated with changes in body composition. One proposed mechanism is that dietary calcium increases fat oxidation, potentially via regulation of serum parathyroid hormone (PTH) concentrations. OBJECTIVES: The objectives of the study were to determine whether acute or chronic increased dairy calcium intakes alter postprandial whole-body fat oxidation and whether the increased intake is related to changes in PTH concentrations. DESIGN: Normal-weight women aged 18-30 y were randomly assigned to a low (<800 mg/d, control; n = 10) or high (1000-1400 mg/d; n = 9) dietary calcium intake group for 1 y. Whole-body fat oxidation was assessed by measuring respiratory gas exchange after each subject consumed 2 isocaloric liquid meals containing 100 or 500 mg Ca at baseline and 1 y. Fasting serum PTH was measured at baseline and 1 y. RESULTS: The mean 1-y change in fat oxidation was higher in the high-calcium group than in the low-calcium control group after a low-calcium meal (0.10 +/- 0.05 compared with 0.005 +/- 0.04 g/min; P < 0.001) and a high-calcium meal (0.06 +/- 0.05 compared with 0.03 +/- 0.04 g/min; P < 0.05). The 1-y change in serum log PTH was negatively associated with the 1-y change in postprandial fat oxidation after a high-calcium meal (partial r = -0.46, P < 0.04) when controlled for the1-y change in total body fat mass. CONCLUSIONS: The results suggest that a chronic diet high in dairy calcium increases whole-body fat oxidation from a meal, and increases in fasting serum PTH relate to decreases in postprandial whole-body fat oxidation.
Authors:
Carolyn W Gunther; Roseann M Lyle; Pamela A Legowski; Julie M James; Linda D McCabe; George P McCabe; Munro Peacock; Dorothy Teegarden
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The American journal of clinical nutrition     Volume:  82     ISSN:  0002-9165     ISO Abbreviation:  Am. J. Clin. Nutr.     Publication Date:  2005 Dec 
Date Detail:
Created Date:  2005-12-07     Completed Date:  2006-01-05     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376027     Medline TA:  Am J Clin Nutr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1228-34     Citation Subset:  AIM; IM    
Affiliation:
Department of Foods & Nutrition, Purdue University, West Lafayette, IN 47907-1264, USA.
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MeSH Terms
Descriptor/Qualifier:
Adipose Tissue / metabolism*
Adolescent
Adult
Basal Metabolism / drug effects,  physiology
Body Composition / drug effects,  physiology
Calcium, Dietary / administration & dosage*,  metabolism
Calorimetry, Indirect
Dairy Products*
Dose-Response Relationship, Drug
Female
Humans
Longitudinal Studies
Oxidation-Reduction
Oxygen Consumption / drug effects,  physiology
Parathyroid Hormone / blood*
Postprandial Period
Chemical
Reg. No./Substance:
0/Calcium, Dietary; 0/Parathyroid Hormone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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