Document Detail

Fat intake and food choices during weight reduction with diet, behavioural modification and a lipase inhibitor.
MedLine Citation:
PMID:  10810001     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To study the composition of fat intake and fat-rich meals consumed during a trial in which obese subjects were treated with a lipase-inhibitor or placebo, with emphasis on food choices and eating hours. DESIGN: Patients were instructed to record all food and drink taken for four days prior to each dietician visit. The food diaries from all scheduled 15 treatment visits were analysed for nutritional content and composition and for temporal distribution. All meals containing 25 g of fat were defined as fat-rich. SUBJECTS: Twenty-eight women and six men, mean age 45.2 +/- 10.9 (SD) years with a mean body mass index of 37.3 +/- 3.3 (SD) kg m-2 at the beginning of the study. RESULTS: Fat intake, both as absolute weight and as energy % was generally higher in the placebo group but no significant trend over time could be seen. Fat rich meals were increased by 59% towards the end of the study. Most fat rich meals were eaten at lunch and dinner. Cooking fat, fatty sauces, meat dishes and cheese contributed to the major proportion of fat, both for placebo and drug treated subjects. No major changes were seen in food choice over time. CONCLUSION: A lipase inhibitor may affect the amount of fat ingested but does not seem to change major sources of fat. The typical fat-rich meal consumed by these subjects was a meat dish, consumed in the evening.
K Franson; S Rössner
Publication Detail:
Type:  Clinical Trial; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of internal medicine     Volume:  247     ISSN:  0954-6820     ISO Abbreviation:  J. Intern. Med.     Publication Date:  2000 May 
Date Detail:
Created Date:  2000-06-19     Completed Date:  2000-06-19     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8904841     Medline TA:  J Intern Med     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  607-14     Citation Subset:  IM    
Swedish Association for People with Bowel and Stomach Diseases, Box 20054, S-104 60 Stockholm, Sweden.
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MeSH Terms
Analysis of Variance
Anti-Obesity Agents / therapeutic use*
Behavior Therapy*
Diet Records
Diet, Reducing*
Dietary Fats / administration & dosage*
Double-Blind Method
Energy Intake
Food Preferences
Lactones / therapeutic use*
Middle Aged
Obesity / prevention & control*
Treatment Outcome
Reg. No./Substance:
0/Anti-Obesity Agents; 0/Dietary Fats; 0/Lactones; 96829-58-2/orlistat

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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