| Fat embolism and the fat embolism syndrome. A double-blind therapeutic study. | |
| | |
MedLine Citation:
|
PMID: 3818718 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Fifty-five adults who had sustained a tibial fracture, or a femoral fracture, or both, were subjected to a double-blind randomised study to determine the efficacy of methylprednisolone in treating the fat embolism syndrome. This drug maintained arterial oxygen levels, stabilised or reduced the serum level of free fatty acids, and decreased the risk of the fat embolism syndrome in a statistically significant proportion of patients. Gurd's criteria for the diagnosis of the fat embolism syndrome were found inadequate. Other more sensitive criteria for early diagnosis and effective management were determined. There were no deaths or serious morbidity in our series. |
| | |
Authors:
|
B G Lindeque; H S Schoeman; G F Dommisse; M C Boeyens; A L Vlok |
Related Documents
:
|
10331588 - Frequency of the fragile x syndrome in chinese mentally retarded populations is similar... 2531158 - Reversible horner's syndrome and lyme disease. 3174078 - Nasal obstruction after cervical sympathectomy: horner's syndrome revisited. 7901988 - Direct dna testing for fragile x syndrome. 20008218 - Clinical approach to marrow failure. 15677408 - The "steroid dementia syndrome": an unrecognized complication of glucocorticoid treatment. |
Publication Detail:
|
Type: Clinical Trial; Journal Article; Randomized Controlled Trial |
Journal Detail:
|
Title: The Journal of bone and joint surgery. British volume Volume: 69 ISSN: 0301-620X ISO Abbreviation: J Bone Joint Surg Br Publication Date: 1987 Jan |
Date Detail:
|
Created Date: 1987-03-30 Completed Date: 1987-03-30 Revised Date: 2010-11-10 |
Medline Journal Info:
|
Nlm Unique ID: 0375355 Medline TA: J Bone Joint Surg Br Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 128-31 Citation Subset: AIM; IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adult Complement C5 / analysis Double-Blind Method Embolism, Fat / diagnosis, drug therapy*, etiology Fatty Acids, Nonesterified / blood Female Femoral Fractures / complications Humans Male Methylprednisolone / therapeutic use* Middle Aged Oxygen / blood Random Allocation Syndrome Tibial Fractures / complications |
| Chemical | |
Reg. No./Substance:
|
0/Complement C5; 0/Fatty Acids, Nonesterified; 7782-44-7/Oxygen; 83-43-2/Methylprednisolone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The Herbert screw for fractures of the scaphoid. A review of results and technical difficulties.
Next Document: Adolescent idiopathic thoracic scoliosis. A prospective trial with and without bracing during postop...