| Fasting serum leptin level correlates with mid-arm fat area in peritoneal dialysis patients. | |
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MedLine Citation:
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PMID: 21118367 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Leptin correlates with body fat content and plays a pivotal role in inflammatory response. This study aimed to investigate the relationships of fasting serum leptin levels and the anthropometric fat components among peritoneal dialysis (PD) patients. Fasting blood samples were obtained from 40 PD patients. Leptin levels were measured using a commercial enzyme-linked immunosorbent assay kit. Body weight (r = 0.424; P = 0.006), waist circumference (r = 0.352; P = 0.026), body mass index (BMI; r = 0.483; P = 0.002), body fat mass (r = 0.352; P = 0.026), high sensitivity C-reactive protein (hs-CRP; r = 0.494; P = 0.001), triceps skinfold thickness (TSF; r = 0.505; P = 0.001), mid-arm circumference (MAC; r = 0.471; P = 0.002), and mid-arm fat area (MAFA; r = 0.564; P < 0.001) were positively correlated, while high density lipoprotein (HDL)-cholesterol (r = -0.345; P = 0.028) was negatively correlated with fasting serum leptin levels among the PD patients. Multivariate forward stepwise linear regression analysis showed that MAFA (R(2) = 0.318, P = 0.011) was the independent predictor of fasting serum leptin levels among the PD patients. In conclusion, fasting leptin level was positively associated with body fat composition (body weight, waist circumference, BMI, body fat mass, TSF, MAC, and MAFA) and hs-CRP among PD patients, and MAFA was the independent predictor of fasting serum leptin levels among the PD patients. |
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Authors:
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Te-Chao Fang; Chung-Jen Lee; Chih-Hsien Wang; Hung-Hsiang Liou; Bang-Gee Hsu |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy Volume: 14 ISSN: 1744-9987 ISO Abbreviation: Ther Apher Dial Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-12-01 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101181252 Medline TA: Ther Apher Dial Country: Australia |
Other Details:
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Languages: eng Pagination: 583-8 Citation Subset: IM |
Copyright Information:
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© 2010 The Authors. Journal compilation © 2010 International Society for Apheresis. |
Affiliation:
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School of Medicine, Tzu Chi University, Division of Nephrology, Buddhist Tzu Chi General Hospital, Department of Nursing, Tzu Chi College of Technology, Hualien, Hsin-Jen Hospital, Taipei, Taiwan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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