Document Detail

Fasting plasma glucose test at the first prenatal visit as a screen for gestational diabetes.
MedLine Citation:
PMID:  12798525     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To determine whether the fasting plasma glucose test administered at the first prenatal visit could serve as an efficient screen for gestational diabetes. METHODS: A total of 5557 women not known to have diabetes were offered a fasting plasma glucose test at their first prenatal visit. Results less than 100 mg/dL were blinded. A glucose tolerance test was requested immediately of those whose screening test result was 100-125 mg/dL and of all women not identified as having diabetes by their 23rd gestational week. RESULTS: A total of 4507 women (81%) complied with the protocol. Of the 302 women found to have gestational diabetes, 46 (15%) were detected before 24 weeks. A false-positive rate of 57% was found at a threshold fasting glucose concentration giving a sensitivity of 80% for the detection of gestational diabetes. CONCLUSION: The fasting plasma glucose screening test at the first prenatal visit has good patient compliance. However, its poor specificity (high false-positive rate) makes it an inefficient screening test for gestational diabetes.
David A Sacks; Wansu Chen; Girma Wolde-Tsadik; Thomas A Buchanan
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Publication Detail:
Type:  Evaluation Studies; Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  101     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  2003 Jun 
Date Detail:
Created Date:  2003-06-11     Completed Date:  2003-07-03     Revised Date:  2010-03-23    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1197-203     Citation Subset:  AIM; IM    
Department of Obstetrics and Gynecology, Kaiser Foundation Hospital, Bellflower, California 90740, USA.
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MeSH Terms
Diabetes, Gestational / diagnosis*
False Positive Reactions
Glucose Tolerance Test*
Mass Screening
Prenatal Care
ROC Curve
Sensitivity and Specificity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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