Document Detail

Fasciola hepatica: collagen deposition and other histopathology in the rat host's bile duct caused by the parasite and by proline infusion.
MedLine Citation:
PMID:  6499998     Owner:  NLM     Status:  MEDLINE    
Bile ducts were examined histochemically to compare the effects of proline infusion with Fasciola hepatica implantation in rats. After 3 weeks of infusion or implantation, both proline and F. hepatica produced increases in the luminal perimeter and collagen content of the bile duct. However, the effect of the parasite was significantly greater than that of proline, and the parasite produced significant increases in the bile duct wall. These results corroborate earlier biochemical and histological studies indicating the important role of proline in the enlargement of the bile duct in fascioliasis.
S Modavi; H Isseroff
Related Documents :
15012778 - Biliary excretion of azelnidipine, a calcium antagonist, in rats.
6673378 - Metabolism and excretion of butein, 2',3,4-trihydroxychalcone, 3-o-methylbutein, 4-o-me...
6499998 - Fasciola hepatica: collagen deposition and other histopathology in the rat host's bile ...
8013278 - Bile flow but not enterohepatic recirculation influences the pharmacokinetics of raniti...
21311188 - The morphology of the rat vibrissal follicle-sinus complex revealed by three-dimensiona...
12633938 - Physical activity prevented age-related decline in energy metabolism in genetically obe...
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Experimental parasitology     Volume:  58     ISSN:  0014-4894     ISO Abbreviation:  Exp. Parasitol.     Publication Date:  1984 Dec 
Date Detail:
Created Date:  1984-12-31     Completed Date:  1984-12-31     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0370713     Medline TA:  Exp Parasitol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  239-44     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Bile Ducts / analysis*,  pathology
Collagen / analysis*
Fasciola hepatica / metabolism*
Fascioliasis / metabolism*,  parasitology,  pathology
Proline / biosynthesis,  pharmacology*
Grant Support
A109911//PHS HHS
Reg. No./Substance:
147-85-3/Proline; 9007-34-5/Collagen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Taenia taeniaeformis: characterization of larval metabolic products and growth of host gastric cells...
Next Document:  Schistosoma mansoni: ultrastructure of adults from mice treated with oxamniquine.