Document Detail


Fasciculations and their F-response revisited: High-density surface EMG in ALS and benign fasciculations.
MedLine Citation:
PMID:  21820354     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
OBJECTIVE: To compare the prevalence of fasciculation potentials (FPs) with F-responses between patients with amyotrophic lateral sclerosis (ALS) and patients with benign fasciculations. METHODS: In seven patients with ALS and seven patients with benign fasciculations, high-density surface EMG was recorded for 15min from the gastrocnemius muscle. Template matching was used to search for pairs of FPs with a repetition within 10-110ms. RESULTS: Interspike interval (ISI) histograms were constructed from 282 pairs of benign fasciculations and from 337 FP pairs in ALS. Peaks attributable to F-waves were found at latencies of 32ms (benign) and 35ms (ALS). Five patients with benign fasciculations and four patients with ALS had FPs with F-waves. CONCLUSIONS: F-waves of FPs occur in both conditions - therefore they are not diagnostically helpful. SIGNIFICANCE: F-waves confirm the distal origin of FPs for an individual axon. The occurrence of these FPs in a benign condition suggests that the generation of ectopic discharges in the distal axons is not specific to progressive neurodegeneration.
Authors:
Bert U Kleine; Werner A Boekestein; Ilse M P Arts; Machiel J Zwarts; H Jurgen Schelhaas; Dick F Stegeman
Related Documents :
2331094 - Oral intubation in the multiply injured patient: the risk of exacerbating spinal cord d...
17400984 - Case series: the mcgrath videolaryngoscope--an initial clinical evaluation.
3257374 - Surgical management of spontaneous pneumothorax in patients with acquired immunodeficie...
18803874 - Post tracheostomy and post intubation tracheal stenosis: report of 31 cases and review ...
9783784 - Elevated arterial base deficit in trauma patients: a marker of impaired oxygen utilizat...
19653174 - Predictors of coronary artery disease in patients with left bundle branch block who und...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-8-3
Journal Detail:
Title:  Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology     Volume:  -     ISSN:  1872-8952     ISO Abbreviation:  -     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-8-8     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100883319     Medline TA:  Clin Neurophysiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.
Affiliation:
Donders Institute for Brain, Cognition and Behaviour, Department of Neurology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Serum antibody response to the gH/gL/pUL128-131 five-protein complex of human cytomegalovirus (HCMV)...
Next Document:  Much ado about the flu: Design and implementation of an e-role play for a large class of undergradua...