Document Detail


Fanconi's syndrome due to ifosfamide.
MedLine Citation:
PMID:  8431714     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Although renal wasting of phosphate is relatively common, Fanconi's syndrome following ifosfamide chemotherapy is rare. This case illustrates the possibility of developing Fanconi's syndrome despite the apparent lack of toxicity during previous ifosfamide exposure. As the use of high-dose ifosfamide-containing regimens prior to BMT increases, the occurrence of this adverse effect may become more frequent. Morbidity due to Fanconi's syndrome can be decreased by close monitoring and aggressive management of fluid and electrolytes.
Authors:
C Beckwith; K K Flaharty; A K Cheung; P G Beatty
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Bone marrow transplantation     Volume:  11     ISSN:  0268-3369     ISO Abbreviation:  Bone Marrow Transplant.     Publication Date:  1993 Jan 
Date Detail:
Created Date:  1993-03-17     Completed Date:  1993-03-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8702459     Medline TA:  Bone Marrow Transplant     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  71-3     Citation Subset:  IM    
Affiliation:
University of Utah College of Pharmacy, Salt Lake City 84112.
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MeSH Terms
Descriptor/Qualifier:
Adult
Bone Marrow Transplantation / adverse effects*
Combined Modality Therapy
Electrolytes / blood
Fanconi Syndrome / chemically induced*,  physiopathology
Female
Humans
Ifosfamide / adverse effects*
Neurilemmoma / drug therapy,  surgery
Water-Electrolyte Balance
Chemical
Reg. No./Substance:
0/Electrolytes; 3778-73-2/Ifosfamide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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