Document Detail

Family transactions and relapse in bipolar disorder.
MedLine Citation:
PMID:  11288369     Owner:  NLM     Status:  MEDLINE    
This study examined whether patient symptoms and relatives' affective behavior, when expressed during directly observed family interactions, are associated with the short-term course of bipolar disorder. Twenty-seven bipolar patients and their relatives participated in two 10-minute family interactions when patients were discharged after a manic episode. Results indicated that patients who showed high levels of odd and grandiose thinking during the interactions were more likely to relapse during a 9-month followup period than patients who did not show these symptoms during the family discussions. Relapse was also associated with high rates of harshly critical and directly supportive statements by relatives. Patients' odd thinking and relatives' harsh criticism were significantly more likely to be correlated when patients relapsed (r = .53) than when they did not relapse (r = .12). Results suggest that bipolar patients who show increased signs of residual symptomatology during family transactions during the post-hospital period are at increased relapse risk. The data also suggest that relatives of relapsing patients cope with these symptoms by increasing both positive and negative affective behaviors. Moreover, a bidirectional, interactional relationship between patients' symptoms and relatives' coping style seems to capture best the role of the family in predicting relapse in bipolar disorder.
I S Rosenfarb; D J Miklowitz; M J Goldstein; L Harmon; K H Nuechterlein; M M Rea
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Family process     Volume:  40     ISSN:  0014-7370     ISO Abbreviation:  Fam Process     Publication Date:  2001  
Date Detail:
Created Date:  2001-04-05     Completed Date:  2001-07-19     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0400666     Medline TA:  Fam Process     Country:  United States    
Other Details:
Languages:  eng     Pagination:  5-14     Citation Subset:  IM    
Department of Psychology and Family Studies, United States International University, 10455 Pomerado Road, San Diego, CA 92131, USA.
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MeSH Terms
Adaptation, Psychological
Bipolar Disorder / physiopathology*,  psychology,  therapy*
Expressed Emotion / classification*
Family Relations*
Family Therapy
Los Angeles
Middle Aged
Psychiatric Status Rating Scales
Sickness Impact Profile
Treatment Outcome
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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