Document Detail

Family case of achalasia cardia: Case report and review of literature.
MedLine Citation:
PMID:  24574786     Owner:  NLM     Status:  In-Data-Review    
Achalasia cardia is an idiopathic disease that occurs as a result of inflammation and degeneration of myenteric plexi leading to the loss of postganglionic inhibitory neurons required for relaxation of the lower esophageal sphincter and peristalsis of the esophagus. The main symptoms of achalasia are dysphagia, regurgitation, chest pain and weight loss. At present, there are three main hypotheses regarding etiology of achalasia cardia which are under consideration, these are genetic, infectious and autoimmune. Genetic theory is one of the most widely discussed. Case report given below represents an inheritable case of achalasia cardia which was not diagnosed for a long time in an 81-year-old woman and her 58-year-old daughter.
Yulia Viktorovna Evsyutina; Alexander Sergeevich Trukhmanov; Vladimir Trophimovich Ivashkin
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  World journal of gastroenterology : WJG     Volume:  20     ISSN:  1007-9327     ISO Abbreviation:  World J. Gastroenterol.     Publication Date:  2014 Jan 
Date Detail:
Created Date:  2014-02-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100883448     Medline TA:  World J Gastroenterol     Country:  China    
Other Details:
Languages:  eng     Pagination:  1114-8     Citation Subset:  IM    
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