Document Detail

Familiality of monocyte esterase deficiency in patients on continuous ambulatory peritoneal dialysis.
MedLine Citation:
PMID:  9713879     Owner:  NLM     Status:  MEDLINE    
The purpose of this study was to determine whether or not peripheral blood monocyte esterase deficiency occurring in patients on CAPD was a familial characteristic. The peripheral blood monocyte esterase status of 74 patients on CAPD was determined by a naphthyl acetate esterase staining of cytospin preparations of their mononuclear cells following separation over ficoll. The peripheral blood of first degree relatives and spouses of monocyte esterase deficiency patients was similarly investigated for the deficiency. Three patients bad monocyte esterase deficiency and familiality of the defect was demonstrated in two of their families. The third family was incompletely investigated because of lack of consent. The monocyte esterase deficiency demonstrated in this cohort of patients did not result from their renal failure but was a familial characteristic.
D R Hull; B R Corr; G M Markey; H D Alexander; T C Morris
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Renal failure     Volume:  20     ISSN:  0886-022X     ISO Abbreviation:  Ren Fail     Publication Date:  1998 Jul 
Date Detail:
Created Date:  1998-11-06     Completed Date:  1998-11-06     Revised Date:  2008-05-21    
Medline Journal Info:
Nlm Unique ID:  8701128     Medline TA:  Ren Fail     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  607-12     Citation Subset:  IM    
Haematology Department, Belfast City Hospital, Northern Ireland.
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MeSH Terms
Cohort Studies
Esterases / blood,  deficiency*
Kidney Failure, Chronic / enzymology,  therapy
Middle Aged
Monocytes / enzymology*
Peritoneal Dialysis, Continuous Ambulatory*
Reg. No./Substance:
EC 3.1.-/Esterases

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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