Document Detail

Familial stroke syndrome associated with mitral valve prolapse.
MedLine Citation:
PMID:  7369719     Owner:  NLM     Status:  MEDLINE    
In a 27-member family, 8 individuals had mitral valve prolapse (MVP) by echocardiography. Four of them suffered a total of eight cerebral ischemic events in the first four decades of life. In none of these patients could risk factors for stroke, other than MVP, be found. Stroke did not occur in individuals free of MVP. This report draws attention to a previously unrecognized cause of familial stroke which strengthens the relationship between MVP and premature stroke.
G P Rice; D R Boughner; C Stiller; G C Ebers
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Annals of neurology     Volume:  7     ISSN:  0364-5134     ISO Abbreviation:  Ann. Neurol.     Publication Date:  1980 Feb 
Date Detail:
Created Date:  1980-06-16     Completed Date:  1980-06-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7707449     Medline TA:  Ann Neurol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  130-4     Citation Subset:  IM    
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MeSH Terms
Aspirin / therapeutic use
HLA Antigens / analysis
Intracranial Embolism and Thrombosis / etiology,  genetics*,  prevention & control
Middle Aged
Mitral Valve Prolapse / genetics*,  immunology
Reg. No./Substance:
0/HLA Antigens; 50-78-2/Aspirin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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