Document Detail


Familial pulmonary hypertension. Evidence of autosomal dominant inheritance.
MedLine Citation:
PMID:  5212347     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A patient with primary pulmonary hypertension is the fourth member of a family proven to have the disease. The patient's father married twice; the disease appeared in both families, and was transmitted through two generations. Multiple genetic and environmental factors may result in pulmonary hypertension, but the distribution of cases in this family and in others reported is consistent with the autosomal dominant inheritance of a single genetic trait.
Authors:
P Thompson; C McRae
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  British heart journal     Volume:  32     ISSN:  0007-0769     ISO Abbreviation:  Br Heart J     Publication Date:  1970 Nov 
Date Detail:
Created Date:  1986-07-08     Completed Date:  1986-07-08     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0370634     Medline TA:  Br Heart J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  758-60     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Genes, Dominant*
Humans
Hypertension, Pulmonary / genetics*,  pathology
Male
Middle Aged
Pedigree
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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