| Familial nephrotic syndrome and HLA-DR5. | |
| | |
MedLine Citation:
|
PMID: 1868484 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Two different types of familial nephrotic syndrome were observed in two unrelated families. In the first family, 2 siblings, both boys without hearing impairment, had proteinuria which was evident after 10 years of age and were resistant to steroid and immunosuppressant therapy. Their renal biopsy findings were compatible with focal-segmental glomerulosclerosis. In the second family, an elder sister and a boy had minimal-change nephrotic syndrome which responded well to steroid and immunosuppressant therapy. All 4 patients had HLA-DR5 in common, suggesting that this gene locus may play an important role in the pathogenesis of familial nephrotic syndrome. |
| | |
Authors:
|
P K Kim; K S Pai; C H Hwang; M S Park; H J Jeong; I J Choi |
Related Documents
:
|
17546704 - Intrafamilial variability in fraser syndrome. 7675414 - Multiple endocrine neoplasia presenting as primary amenorrhea: a case report. 15200504 - Familial iridogoniodysgenesis and skeletal anomalies: a probable new autosomal recessiv... 6696034 - Leber's congenital amaurosis associated with familial juvenile nephronophthisis and con... 1341424 - Ectodermal dysplasias associated with clefting: significance of scalp dermatitis. 1990464 - Wernicke-korsakoff syndrome complicating t-cell lymphoma: unusual or unrecognized? |
Publication Detail:
|
Type: Case Reports; Journal Article |
Journal Detail:
|
Title: Child nephrology and urology Volume: 11 ISSN: 1012-6694 ISO Abbreviation: Child Nephrol Urol Publication Date: 1991 |
Date Detail:
|
Created Date: 1991-09-13 Completed Date: 1991-09-13 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 8910177 Medline TA: Child Nephrol Urol Country: SWITZERLAND |
Other Details:
|
Languages: eng Pagination: 55-60 Citation Subset: IM |
Affiliation:
|
Department of Pediatrics, Yonsei University College of Medicine, Seoul, Korea. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Child Fanconi Syndrome Female Glomerulosclerosis, Focal Segmental / genetics*, pathology HLA-DR5 Antigen / genetics* Humans Infant Kidney Glomerulus / pathology Male Nephrosis, Lipoid / genetics*, pathology |
| Chemical | |
Reg. No./Substance:
|
0/HLA-DR5 Antigen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Pitfalls in the treatment of congenital urologic anomalies.
Next Document: Relations between hypertension and glomerulosclerosis in first-generation hybrid rats of the Milan s...