Document Detail


Familial myoedema, muscular hypertrophy and stiffness.
MedLine Citation:
PMID:  2353568     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A father and son with muscular hypertrophy, stiffness and myoedema are described. The local swelling after tapping the muscle was not accompanied by electrical activity. Histological and histochemical studies of muscle biopsy showed no abnormalities. Electron-microscopy showed multiple vacuoles to be due to T-tubule dilatation. Further studies are necessary to determine the significance of this finding in the pathogenesis of muscle sensitivity to mechanical irritation in this rare syndrome.
Authors:
M Sadeh; M Berg; U Sandbank
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta neurologica Scandinavica     Volume:  81     ISSN:  0001-6314     ISO Abbreviation:  Acta Neurol. Scand.     Publication Date:  1990 Mar 
Date Detail:
Created Date:  1990-07-17     Completed Date:  1990-07-17     Revised Date:  2006-08-16    
Medline Journal Info:
Nlm Unique ID:  0370336     Medline TA:  Acta Neurol Scand     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  201-4     Citation Subset:  IM    
Affiliation:
Department of Neurology, Chaim Sheba Medical Center, Tel Hashomer, Israel.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Edema / complications,  genetics*,  physiopathology
Humans
Hypertrophy
Male
Muscle Rigidity / complications,  genetics*,  physiopathology
Muscular Diseases / genetics*,  pathology,  physiopathology
Syndrome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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